If you want to use a slow cooker, cooking times are 5-6 hours on High and 7-8 hours on Low, depending on how thick and what cut your beef is. Add the vegetables about 1 hour before the meat is finished so you have enough time to cook the firm potatoes and carrots.
Please refer to your specific pressure cooker manual for complete product cooking use. Every model and brand will be slightly different. If your pressure cooker does not have a searing function, you can pre-sear on a pan over the cooktop or just skip the searing steps. This recipe was tested in the 6qt. Instant Pot.